Among the conservation problems of the pieces as a whole, there was a common darkening caused by the deposition of particulate matter and to the alteration of superimposed substances; there were also stains of various kinds, including iron oxides. More recent restorations used polyester resin and plaster for bonding detached parts or recompositions. On most of the fragments, visible surface scratches are identified. The reintegrations were in cement mortar or plaster. In the preparatory phase of the restoration, the Scientific Research Laboratory of the Vatican Museums conducted scientific investigations. In cleaning the pieces, the restorer used a combination of various methodologies, examining, analyzing, and preserving traces of polychromy and patinas. Alongside the restoration operations, photographic documentation and cataloging were carried out. Mentioned below are some works that specifically required diversified operations and in-depth investigations. During the restoration of sarcophagus case MV_31406, following the removal of the lid, it became evident that a conspicuous fragment, probably part of an early medieval pluteus, carved in bas-relief with phytomorphic decorative motifs, was used as an addition to a fragmentary part of it during a 19th-century restoration.

The piece MV_31597, which has been the subject of a relatively recent restoration, of which there is no record, however, except in the material evidence, had in the central median band an area characterized by differential degradation with a horizontal trend, which created a drastic darkening of the surface. The cleaning involved repeated applications of Agar Agar in deionized water with 0.5 percent tri ammonium citrate followed by applications limited to the median band of zeolite and deionized water until dry and mechanical removal of the product by dusting. The post-rubrication was removed in successive and punctual passes by swabbing with acetone. Next, localized consolidations were determined to be performed on the fascia with differential degradation by infiltration of nanocalcium in isopropanol. To conclude, grouting was carried out, specifically in the center of the central tabula with the sepulchral inscription, with mortar based on fine-grained marble powder and lime putty, followed by color balancing with ventilated earth.